Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromothiophene-2-carboxylic acid

  • CAS No. 7311-64-0

  • Cat. No. CS-W004773
  • Purity≥98%
  • MDL No.MFCD00052291

*For research and further manufacturing use only, not for direct human use.

3-Bromothiophene-2-carboxylic acid|CS-W004773

Structure of 7311-64-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 7311-64-0
  • Cat. No. CS-W004773
  • Purity ≥98%
  • MDL No. MFCD00052291
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrO₂S
  • Molecular Weight 207.05
  • Synonym(s) 3-bromothiophene-2-carboxylate
  • SMILES O=C(C1=C(Br)C=CS1)O

Description

3-Bromothiophene-2-carboxylic acid delivers a brominated thiophene scaffold with a carboxylic acid handle, enabling direct coupling in cross-coupling and functionalization workflows. The electron-deficient ring facilitates palladium-catalyzed transformations, while the acidic proton supports derivatization under mild conditions. This bench-stable reagent integrates seamlessly into synthetic sequences requiring halogenated heterocycles.

Application

3-Bromothiophene-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates derivatization via amide formation, esterification, or decarboxylative functionalization. The compound exhibits good bench stability and is compatible with standard synthetic workflows, enabling efficient access to substituted thiophene scaffolds relevant to medicinal chemistry and materials science.

Synthesis

  • Route1
    • In-stock
      2,3-Dibromothiophene|CS-W019996
      3140-93-0
    • null|null
      124-38-9
    • ~91%
    • In-stock
      3-Bromothiophene-2-carboxylic acid|CS-W004773
      7311-64-0

    References

    • E.T.C. S.R.L.; MELUCCI, Manuela; FAVARETTO, Laura; ZAMBIANCHI, Massimo; CAPELLI, Raffaella; MUCCINI, Michele Patent: WO2012/156948 A1, 2012 ; Location in patent: Page/Page column 21-22 ;
  • Route2

    References

    • Hendrix, James A.; Strupczewski, Joseph T.; Bordeau, Kenneth J.; Brooks, Sarah; Hemmerle, Horst; Urmann, Matthias; Zhao, Xu-Yang; Mueller, Paul J. Patent: US2003/229066 A1, 2003 ; Location in patent: Page 45 ; US 20030229066 A1
  • Route3
    • In-stock
      3-Bromothiophene|CS-W009226
      872-31-1
    • null|null
      124-38-9
    • ~18%
    • In-stock
      3-Bromothiophene-2-carboxylic acid|CS-W004773
      7311-64-0

    References

    • Nemoto, Koji; Onozawa, Satoru; Konno, Megumi; Morohashi, Naoya; Hattori, Tetsutaro Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 3 p. 369 - 371

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317
Precautionary Statements : P261-P272-P280-P302+P352-P363-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2088
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Bromothiophene-2-carboxylic acid sigma3-Bromothiophene-2-carboxylic acid manufacturer3-Bromothiophene-2-carboxylic acid price3-Bromothiophene-2-carboxylic acid structure3-Bromothiophene-2-carboxylic acid SDSbuy 3-Bromothiophene-2-carboxylic acid3-Bromothiophene-2-carboxylic acid supplier3-Bromothiophene-2-carboxylic acid uses3-Bromothiophene-2-carboxylic acid molecular weightprice of 3-Bromothiophene-2-carboxylic acid3-Bromothiophene-2-carboxylic acid chemical name formula of 3-Bromothiophene-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label