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CS-W001157 4
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5-Bromo-2-thiophenecarboxylic acid

  • CAS No. 7311-63-9

  • Cat. No. CS-B0139
  • Purity≥96%
  • MDL No.MFCD00079725

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-thiophenecarboxylic acid|CS-B0139

Structure of 7311-63-9

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General Information

  • CAS No. 7311-63-9
  • Cat. No. CS-B0139
  • Purity ≥96%
  • MDL No. MFCD00079725
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrO₂S
  • Molecular Weight 207.05
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C(Br)S1

Description

5-Bromo-2-thiophenecarboxylic acid features a brominated thiophene core with a carboxylic acid group at the 2-position, enabling direct functionalization in cross-coupling and conjugation workflows. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and advanced materials, offering enhanced reactivity under standard conditions.

Synthesis

  • Route1

    References

    • Shih, Chuan; Gossett, Lynn S.; Worzalla, John F.; Rinzel, Sharon M.; Grindey, Gerald B.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 1109 - 1116
  • Route2

    References

    • Karminski-Zamola, Grace; Dogan, Jasna; Bajic, Miroslav; Blazevic, Jelena; Malesevic, Miroslav Heterocycles, 1994 , vol. 38, # 4 p. 759 - 768
  • Route3
    • null|null
      3141-27-3
    • null|null
      124-38-9
    • ~89%
    • In-stock
      5-Bromo-2-thiophenecarboxylic acid|CS-B0139
      7311-63-9

    References

    • Sell; Hanson; Rieke Synthetic Communications, 1994 , vol. 24, # 16 p. 2379 - 2386

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2088
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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