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CS-W001157 4
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tert-Butyl (5-fluorothiazol-2-yl)carbamate

  • CAS No. 731018-54-5

  • Cat. No. CS-0039072
  • Purity≥97%
  • MDL No.MFCD11656630

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (5-fluorothiazol-2-yl)carbamate|CS-0039072

Structure of 731018-54-5

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General Information

  • CAS No. 731018-54-5
  • Cat. No. CS-0039072
  • Purity ≥97%
  • MDL No. MFCD11656630
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁FN₂O₂S
  • Molecular Weight 218.25
  • Synonym(s) tert-butyl (5-fluoro-1,3-thiazol-2-yl)carbamate
  • SMILES CC(C)(C)OC(=NC1=NC=C(F)S1)O

Synthesis

  • Route1

    References

    • TAKEDA SAN DIEGO, INC.; MATTSON, Matthew Patent: WO2011/115758 A1, 2011 ; Location in patent: Page/Page column 14 ;
  • Route2

    References

    • Briner, Paul H.; Fyfe, Matthew C. T.; Martin, Pierre; Murray, P. John; Naud, Frederic; Procter, Martin J. Organic Process Research and Development, 2006 , vol. 10, # 2 p. 346 - 348
  • Route3

    References

    • Cheruvallath, Zacharia; Feng, Jun; Guntupalli, Prasuna; Gwaltney, Stephen L.; Kaldor, Stephen W.; Miura, Joanne; Sabat, Mark; Tang, Mingnam; Wolgast, Beverly Patent: US2007/213349 A1, 2007 ; Location in patent: Page/Page column 67 ; US 20070213349 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.71
  • LogP   2.6428
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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