Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-(4-Bromophenyl)oxazole

  • CAS No. 72571-06-3

  • Cat. No. CS-0187063
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-(4-Bromophenyl)oxazole|CS-0187063

Structure of 72571-06-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 72571-06-3
  • Cat. No. CS-0187063
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆BrNO
  • Molecular Weight 224.05
  • Synonym(s) 5-(4-Bromophenyl)-1,3-oxazole
  • SMILES BrC1=CC=C(C2=CN=CO2)C=C1

Description

5-(4-Bromophenyl)oxazole is a bench-stable heterocyclic scaffold featuring a brominated phenyl group at the 5-position, enabling direct functionalization in cross-coupling reactions. This electron-deficient oxazole integrates readily into advanced synthetic intermediates for pharmaceuticals and materials science.

Application

5-(4-Bromophenyl)oxazole serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biaryl architectures. The bromine substituent provides high reactivity in standard Suzuki, Stille, and Negishi couplings, while the oxazole ring offers metabolic stability and favorable electronic properties for medicinal chemistry applications. Bench-stable and readily purified by flash chromatography, it functions efficiently in modular synthesis of functionalized heterocycles and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      38622-91-2
    • In-stock
      4-Bromobenzaldehyde|CS-W001138
      1122-91-4
    • ~%
    • In-stock
      5-(4-Bromophenyl)oxazole|CS-0187063
      72571-06-3

    References

    • Tetrahedron Letters, , vol. 50, # 26 p. 3273 - 3276
  • Route2
    • null|null
      55605-27-1
    • null|null
      38622-91-2
    • ~88%
    • In-stock
      5-(4-Bromophenyl)oxazole|CS-0187063
      72571-06-3

    References

    • Ding, Zhenhua; Yoshikai, Naohiko Organic Letters, 2010 , vol. 12, # 18 p. 4180 - 4183
  • Route3
    • Ethyl 5-(4-bromophenyl)oxazole-2-carboxylate|CS-0670819
      72571-05-2
    • ~58%
    • In-stock
      5-(4-Bromophenyl)oxazole|CS-0187063
      72571-06-3

    References

    • Morton-Norwich Products, Inc. Patent: US4171307 A1, 1979 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.03
  • LogP   3.1041
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-(4-Bromophenyl)oxazole sigma5-(4-Bromophenyl)oxazole manufacturer5-(4-Bromophenyl)oxazole price5-(4-Bromophenyl)oxazole structure5-(4-Bromophenyl)oxazole SDSbuy 5-(4-Bromophenyl)oxazole5-(4-Bromophenyl)oxazole supplier5-(4-Bromophenyl)oxazole uses5-(4-Bromophenyl)oxazole molecular weightprice of 5-(4-Bromophenyl)oxazole5-(4-Bromophenyl)oxazole chemical name formula of 5-(4-Bromophenyl)oxazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label