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CS-W001157 4
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rel-(1R,2R,4S)-Bicyclo[2.2.1]heptan-2-amine

  • CAS No. 7242-92-4

  • Cat. No. CS-0119860
  • Purity≥97%
  • MDL No.MFCD00078132

*For research and further manufacturing use only, not for direct human use.

rel-(1R,2R,4S)-Bicyclo[2.2.1]heptan-2-amine|CS-0119860

Structure of 7242-92-4

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General Information

  • CAS No. 7242-92-4
  • Cat. No. CS-0119860
  • Purity ≥97%
  • MDL No. MFCD00078132
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃N
  • Molecular Weight 111.18
  • Synonym(s) exo-2-Aminonorbornane
  • SMILES N[C@H]1[C@@H](C2)CC[C@@H]2C1

Description

rel-(1R,2R,4S)-Bicyclo[2.2.1]heptan-2-amine features a rigid, bridged bicyclic scaffold with defined stereochemistry at the 1R,2R,4S positions. This configuration imparts high conformational stability and predictable spatial orientation, making it valuable for asymmetric synthesis and as a chiral building block in medicinal chemistry.

Application

rel-(1R,2R,4S)-Bicyclo[2.2.1]heptan-2-amine serves as a rigid, chiral building block for medicinal chemistry and asymmetric synthesis. Its defined stereochemistry and stable bicyclic framework enable predictable reactivity in functional group transformations and facilitate the construction of complex heterocyclic scaffolds. The amine functionality supports facile derivatization, including amidation and alkylation, while the molecule exhibits excellent bench stability and ease of purification—making it well-suited for high-throughput screening and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2733
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.7698
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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