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Structure of 72235-55-3
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(3-Chloro-2-fluorophenyl)methanamine is a fluorinated arylalkylamine featuring ortho-chloro and meta-fluoro substitution on the phenyl ring. This electron-deficient aromatic scaffold enables efficient coupling in cross-coupling and amide-forming reactions. The primary amine group offers direct functionalization potential, while the halogenated framework enhances metabolic stability and lipophilicity in bioactive molecule design.
(3-Chloro-2-fluorophenyl)methanamine serves as a valuable building block for bioactive heterocycles and pharmaceutical intermediates, enabling direct incorporation of ortho-fluoro-chloro aryl motifs. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of functionalized anilines, pyridines, and fused ring systems relevant to medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P280-P301+P330+P331-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: