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Methyl (S)-3-amino-2-hydroxypropanoate hydrochloride

  • CAS No. 72185-81-0

  • Cat. No. CS-0131698
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (S)-3-amino-2-hydroxypropanoate hydrochloride|CS-0131698

Structure of 72185-81-0

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General Information

  • CAS No. 72185-81-0
  • Cat. No. CS-0131698
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO₃
  • Molecular Weight 155.58
  • Synonym(s) (S)-methyl 3-amino-2-hydroxypropanoate hydrochloride
  • SMILES NC[C@H](O)C(OC)=O.[H]Cl

Description

Methyl (S)-3-amino-2-hydroxypropanoate hydrochloride features a chiral α-amino alcohol scaffold with enhanced solubility and stability under standard conditions. This bench-stable derivative integrates seamlessly into peptide backbone modifications and serves as a key building block for bioactive molecule synthesis. The protected amine and hydroxyl groups enable selective derivatization in complex reaction sequences.

Application

Methyl (S)-3-amino-2-hydroxypropanoate hydrochloride serves as a chiral building block for peptide mimetics and bioactive heterocycles. Its amino and hydroxyl groups enable orthogonal functionalization, while the methyl ester facilitates downstream derivatization. The hydrochloride salt enhances bench stability and solubility, supporting efficient synthesis in standard amide coupling and cyclization protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   -1.0992
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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