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CS-W001157 4
Total: USD 88.00

5-Amino-3H-imidazole-4-carboxamide hydrochloride

  • CAS No. 72-40-2

  • Cat. No. CS-M3470
  • Purity≥97%
  • MDL No.MFCD00012704

*For research and further manufacturing use only, not for direct human use.

5-Amino-3H-imidazole-4-carboxamide hydrochloride|CS-M3470

Structure of 72-40-2

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General Information

  • CAS No. 72-40-2
  • Cat. No. CS-M3470
  • Purity ≥97%
  • MDL No. MFCD00012704
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClN₄O
  • Molecular Weight 162.58
  • Synonym(s) 5-Aminoimidazole-4-carboxamide (hydrochloride); AICA (hydrochloride)
  • SMILES O=C(C1=C(N)NC=N1)N.[H]Cl

Description

Corrosion inhibition and adsorption characteristics of 5-amino-4-imidazolecarboxamide hydrochloride on aluminum in 1M HCl has been investigated.5-Amino-4-imidazolecarboxamide hydrochloride was used in the synthesis of heterocyclic compounds such as guanine, purines and pyrimidines.

Application

5-Amino-3H-imidazole-4-carboxamide (hydrochloride) serves as a versatile building block in heterocyclic synthesis, enabling efficient access to imidazole-based scaffolds prevalent in medicinal chemistry. The compound exhibits robust bench stability and facilitates straightforward functionalization at both the amino and carboxamide positions, supporting diverse coupling and cyclization reactions. Its well-defined reactivity profile makes it particularly valuable for constructing bioactive core structures under standard synthetic conditions.

Synthesis

  • Route1
    • 5-Amino-3H-imidazole-4-Carboxamide Temozolomide  Impurity|CS-0229320
      360-97-4
    • ~%
    • In-stock
      5-Amino-3H-imidazole-4-carboxamide hydrochloride|CS-M3470
      72-40-2
    • 4-Diazo-4H-imidazole-5-carboxamide|CS-0654577
      7008-85-7

    References

    • US2011/230658 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   97.79
  • LogP   -0.4874
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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