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Structure of 711-33-1
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1-(4-(Trifluoromethyl)phenyl)propan-1-one features a conjugated aryl-ketone system with a strongly electron-withdrawing trifluoromethyl group, enhancing electrophilicity at the carbonyl center. This bench-stable ketone integrates readily into C–C bond formation strategies and serves as a key building block in pharmaceutical synthesis and materials chemistry.
1-(4-(Trifluoromethyl)phenyl)propan-1-one serves as a valuable building block in medicinal chemistry, enabling the synthesis of biologically active compounds through established carbonyl transformations. Its trifluoromethyl aryl group enhances metabolic stability and lipophilicity, while the ketone functionality supports efficient conjugate additions, reductions, and coupling reactions. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: