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CS-W001157 4
Total: USD 88.00

1-(4-(Trifluoromethyl)phenyl)ethanone

  • CAS No. 709-63-7

  • Cat. No. CS-W007473
  • Purity≥97%
  • MDL No.MFCD00000401

*For research and further manufacturing use only, not for direct human use.

1-(4-(Trifluoromethyl)phenyl)ethanone|CS-W007473

Structure of 709-63-7

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General Information

  • CAS No. 709-63-7
  • Cat. No. CS-W007473
  • Purity ≥97%
  • MDL No. MFCD00000401
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇F₃O
  • Molecular Weight 188.15
  • Synonym(s) Sodium4-trifluoromethylbenzoate
  • SMILES C1=C(C=CC(=C1)C(C)=O)C(F)(F)F

Description

1-(4-(Trifluoromethyl)phenyl)ethanone features a trifluoromethyl-substituted aryl ring conjugated to a ketone group, delivering enhanced electron-withdrawing character and improved metabolic stability. This structure facilitates efficient incorporation into pharmaceutical intermediates and functional materials under standard conditions.

Synthesis

  • Route1

    References

    • Zhu, Feng-Xia; Wang, Wei; Li, He-Xing Journal of the American Chemical Society, 2011 , vol. 133, # 30 p. 11632 - 11640
  • Route2

    References

    • Wang, Qingfu; Du, Wangming; Liu, Tingting; Chai, Huining; Yu, Zhengkun Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1585 - 1588
  • Route3
    • null|null
      108-24-7
    • null|null
      2786-01-8
    • ~95%
    • In-stock
      1-(4-(Trifluoromethyl)phenyl)ethanone|CS-W007473
      709-63-7

    References

    • Wehle, Detlef; Forstinger, Klaus; Meudt, Andreas Patent: US2005/1333 A1, 2005 ; Location in patent: Page/Page column 3, 4 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.908
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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