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CS-W001157 4
Total: USD 88.00

3,6-Dichloro-4-methoxypyridazine

  • CAS No. 70952-62-4

  • Cat. No. CS-W018958
  • Purity≥96%
  • MDL No.MFCD00477252

*For research and further manufacturing use only, not for direct human use.

3,6-Dichloro-4-methoxypyridazine|CS-W018958

Structure of 70952-62-4

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General Information

  • CAS No. 70952-62-4
  • Cat. No. CS-W018958
  • Purity ≥96%
  • MDL No. MFCD00477252
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₂O
  • Molecular Weight 179.00
  • Synonym(s) 3,6-dichloro-4-methoxypyridazin
  • SMILES COC1=CC(Cl)=NN=C1Cl

Description

3,6-Dichloro-4-methoxypyridazine is a halogenated pyridazine derivative featuring two chlorine substituents at the 3- and 6-positions and a methoxy group at the 4-position. This electron-deficient heterocycle serves as a key building block in medicinal chemistry, enabling efficient coupling reactions and facilitating the synthesis of bioactive compounds through its reactive sites.

Application

3,6-Dichloro-4-methoxypyridazine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution. The dichloro pattern facilitates sequential functionalization at C3 and C6 positions, while the methoxy group offers orthogonal reactivity and enhanced solubility. Its bench-stable nature and compatibility with standard coupling conditions make it ideal for modular synthesis workflows targeting API intermediates.

Synthesis

  • Route1

    References

    • Helvetica Chimica Acta, , vol. 39, p. 1755,1762

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.01
  • LogP   1.792
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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