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Structure of 7079-15-4
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4'-Chloro-[1,1'-biphenyl]-2-carboxylic acid features a chlorinated aryl group paired with a carboxylic acid functionality, enabling direct integration into Suzuki-Miyaura coupling reactions. The electron-withdrawing chlorine enhances reactivity at the para position, while the carboxylic acid serves as a handle for derivatization. This compound offers bench-stable handling and compatibility with standard cross-coupling conditions.
4'-Chloro-[1,1'-biphenyl]-2-carboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation of ortho-substituted biphenyl motifs into bioactive scaffolds. Its carboxylic acid functionality facilitates amide coupling, esterification, and metal-catalyzed transformations under standard conditions. The chloro substituent provides a handle for further functionalization via palladium-catalyzed cross-coupling reactions. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring orthogonal reactivity and structural rigidity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: