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Structure of 7043-11-0
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4-Chloro-2-cyclopropyl-6-methylpyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and favorable lipophilicity. The cyclopropyl group imparts conformational rigidity, while the chloro and methyl substituents enable strategic electronic tuning for target engagement. This compound integrates efficiently into kinase inhibitor frameworks and other bioactive molecules under standard conditions.
4-Chloro-2-cyclopropyl-6-methylpyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chloro group facilitates palladium-catalyzed cross-coupling reactions, while the cyclopropyl and methyl substituents provide steric and electronic tuning for target-specific optimization. The compound exhibits good bench stability and compatibility with standard purification methods, making it suitable for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: