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CS-W001157 4
Total: USD 88.00

Tris(2-(2-methoxyethoxy)ethyl)amine

  • CAS No. 70384-51-9

  • Cat. No. CS-W008173
  • Purity≥95%
  • MDL No.MFCD00010748

*For research and further manufacturing use only, not for direct human use.

Tris(2-(2-methoxyethoxy)ethyl)amine|CS-W008173

Structure of 70384-51-9

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General Information

  • CAS No. 70384-51-9
  • Cat. No. CS-W008173
  • Purity ≥95%
  • MDL No. MFCD00010748
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₃NO₆
  • Molecular Weight 323.43
  • Synonym(s) Tris(dioxa-3,6-heptyl)amine
  • SMILES COCCOCCN(CCOCCOC)CCOCCOC

Description

Tris[2-(2-methoxyethoxy)ethyl]amine was used:in oxidation of arylmethanols under phase-transfer conditionsas cryptand during phase-transfer glycosylation of 2-amino-4-methoxy-7H-pyrrolo[2,3-d]pyrimidineas phase-transfer catalyst in synthesis of 1,3-dideaza-2-deoxyadenosine and related benzimidazole 2-deoxyribonucleosides

Application

Tris(2-(2-methoxyethoxy)ethyl)amine serves as a robust, bench-stable ligand in transition metal-catalyzed cross-coupling reactions, offering excellent solubility in polar aprotic solvents and tolerance to diverse functional groups. Its ether-rich structure facilitates coordination to palladium and nickel centers, enabling efficient catalytic turnover in Suzuki-Miyaura and Negishi couplings. The molecule’s low toxicity profile and ease of purification make it well-suited for scalable synthetic applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 40, # 7 p. 1611 - 1616,1598 - 1602
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 50, # 20 p. 3717 - 3721
  • Route3
    • 1-Chloro-2-(2-methoxyethoxy)ethane|CS-0700581
      52808-36-3
    • ~%
    • In-stock
      Tris(2-(2-methoxyethoxy)ethyl)amine|CS-W008173
      70384-51-9

    References

    • J. Gen. Chem. USSR (Engl. Transl.), , vol. 40, # 7 p. 1611 - 1616,1598 - 1602

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   58.62
  • LogP   0.2774
  • H_Acceptors   7
  • H_Donors   0
  • Rotatable_Bonds   18

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