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CS-W001157 4
Total: USD 88.00

4-(4-Methylpiperazin-1-ylmethyl)phenylamine

  • CAS No. 70261-82-4

  • Cat. No. CS-W005018
  • Purity≥95%
  • MDL No.MFCD03725418

*For research and further manufacturing use only, not for direct human use.

4-(4-Methylpiperazin-1-ylmethyl)phenylamine|CS-W005018

Structure of 70261-82-4

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General Information

  • CAS No. 70261-82-4
  • Cat. No. CS-W005018
  • Purity ≥95%
  • MDL No. MFCD03725418
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉N₃
  • Molecular Weight 205.30
  • Synonym(s) 4-[(4-Methylpiperazin-1-yl)methyl]aniline
  • SMILES NC1=CC=C(CN2CCN(C)CC2)C=C1

Description

This 4-(4-methylpiperazin-1-ylmethyl)phenylamine features a piperazine-linked arylamine scaffold with enhanced solubility and nucleophilicity. The methylpiperazine moiety imparts favorable pharmacokinetic properties, while the para-aminomethyl phenyl group enables efficient coupling in bioconjugation and medicinal chemistry applications.

Synthesis

  • Route1
    • 1-Methyl-4-(4-nitrobenzyl)piperazine|CS-W002721
      70261-81-3
    • ~99%
    • In-stock
      4-(4-Methylpiperazin-1-ylmethyl)phenylamine|CS-W005018
      70261-82-4

    References

    • European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2917 - 2929
  • Route2

    References

    • Medicinal Chemistry Research, , vol. 9, # 3 p. 149 - 161
  • Route3
    • null|null
      100-11-8
    • ~%
    • In-stock
      4-(4-Methylpiperazin-1-ylmethyl)phenylamine|CS-W005018
      70261-82-4

    References

    • Medicinal Chemistry Research, , vol. 9, # 3 p. 149 - 161

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.5
  • LogP   1.0162
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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