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CS-W001157 4
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7-chloro-benzothiazol-6-ylamine

  • CAS No. 70202-00-5

  • Cat. No. CS-0155796
  • Molecule weight184.65
  • Purity≥98%
  • MDL No.MFCD18822308

*For research and further manufacturing use only, not for direct human use.

7-chloro-benzothiazol-6-ylamine|CS-0155796

Structure of 70202-00-5

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General Information

  • CAS No. 70202-00-5
  • Cat. No. CS-0155796
  • Purity ≥98%
  • MDL No. MFCD18822308
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClN₂S
  • Molecular Weight 184.65
  • Synonym(s) 6-Benzothiazolamine,7-chloro-(9CI)
  • SMILES C1=CC2=C(C(=C1N)Cl)SC=N2

Description

7-Chloro-benzothiazol-6-ylamine features a chlorinated benzothiazole core with a primary amine at the 6-position, enabling direct coupling in heterocyclic synthesis. This electron-deficient scaffold integrates readily into bioactive molecules, offering enhanced metabolic stability and improved solubility profiles under standard conditions.

Application

7-Chloro-benzothiazol-6-ylamine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient access to pharmaceutical scaffolds via coupling reactions. Its reactive primary amine and electron-deficient benzothiazole core facilitate straightforward functionalization under standard conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for medicinal chemistry campaigns requiring rapid diversification.

Synthesis

  • Route1

    References

    • Synaptic Pharmaceutical Corporation Patent: US5677321 A1, 1997 ; US 5677321 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.5319
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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