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CS-W001157 4
Total: USD 88.00

Trimethylhydroquinone

  • CAS No. 700-13-0

  • Cat. No. CS-W018094
  • Purity≥97%
  • MDL No.MFCD00002346

*For research and further manufacturing use only, not for direct human use.

Trimethylhydroquinone|CS-W018094

Structure of 700-13-0

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General Information

  • CAS No. 700-13-0
  • Cat. No. CS-W018094
  • Purity ≥97%
  • MDL No. MFCD00002346
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₂
  • Molecular Weight 152.19
  • Synonym(s) None
  • SMILES OC1=CC(C)=C(O)C(C)=C1C

Description

t-Boc-Aminooxy-PEG4-CH2CO2H is a crosslinking reagent with a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU). The Boc-protected amine can be deprotected under mild acidic conditions. PEG4 spacer increases solubility in aqueous media.

Application

Trimethylhydroquinone serves as a stable, bench-accessible phenolic building block enabling selective functionalization in complex molecule synthesis. Its three methyl groups confer enhanced solubility and resistance to oxidation, facilitating purification and handling. Functions as a versatile scaffold in the construction of bioactive heterocycles and antioxidant derivatives through standard coupling and electrophilic substitution protocols.

Synthesis

  • Route1
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    • In-stock
      Trimethylhydroquinone|CS-W018094
      700-13-0

    References

    • WO2012/25587 A1, ; Page/Page column 34-35 ;
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    References

    • Weerapreeyakul, Natthida; Visser, Petra; Brummelhuis, Mathijn; Gharat, Laxmikant; Chikhale, Prashant J. Medicinal Chemistry Research, 2000 , vol. 10, # 3 p. 148 - 163
  • Route3
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      56621-35-3
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      71-36-3
    • ~%
    • In-stock
      Trimethylhydroquinone|CS-W018094
      700-13-0

    References

    • US5969176 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H317-H318-H332-H335-H410
Precautionary Statements : P261-P264-P271-P272-P273-P280-P302+P352-P304+P340-P362+P364-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   2.02306
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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