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CS-W001157 4
Total: USD 88.00

2,3,5-Trimethylphenol

  • CAS No. 697-82-5

  • Cat. No. CS-W016528
  • Purity≥98%
  • MDL No.MFCD00002228

*For research and further manufacturing use only, not for direct human use.

2,3,5-Trimethylphenol|CS-W016528

Structure of 697-82-5

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General Information

  • CAS No. 697-82-5
  • Cat. No. CS-W016528
  • Purity ≥98%
  • MDL No. MFCD00002228
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O
  • Molecular Weight None
  • Synonym(s) Isopseudocumenol
  • SMILES CC(C=C1O)=CC(C)=C1C

Description

2,3,5-Trimethylphenol features a sterically hindered aromatic ring with three methyl groups positioned to enhance solubility and thermal stability. This electron-rich phenolic scaffold enables efficient coupling reactions and serves as a key building block in specialty polymer synthesis and agrochemical intermediates.

Application

2,3,5-Trimethylphenol serves as a versatile building block in synthetic organic chemistry, offering enhanced stability and predictable regioselectivity due to its sterically hindered yet electron-rich aromatic framework. It functions reliably in electrophilic substitution, etherification, and coupling reactions, enabling efficient access to substituted phenolic scaffolds. Its bench-stable nature and straightforward purification make it ideal for iterative synthesis workflows in medicinal chemistry and materials development.

Synthesis

  • Route1
    • null|null
      312609-91-9
    • ~89%
    • In-stock
      2,3,5-Trimethylphenol|CS-W016528
      697-82-5

    References

    • Nayak Synthesis, 2000 , # 11 p. 1575 - 1578
  • Route2
    • null|null
      68097-90-5
    • ~%
    • In-stock
      2,3,5-Trimethylphenol|CS-W016528
      697-82-5

    References

    • Journal of the Chemical Society, , p. 400,403
  • Route3
    • 3,5-Dimethyl-2-(morpholinomethyl)phenol|CS-0513429
      14944-83-3
    • ~%
    • In-stock
      2,3,5-Trimethylphenol|CS-W016528
      697-82-5

    References

    • Journal of the American Chemical Society, , vol. 61, p. 765

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2430
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P280-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.31746
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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