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Structure of 69947-09-7
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1,4-Dioxaspiro[4.5]decane-8-carbonitrile features a rigid spirocyclic core with two ether linkages and a terminal nitrile group, enabling precise spatial positioning in molecular architectures. This bench-stable scaffold integrates readily into complex synthetic sequences, offering enhanced solubility and controlled reactivity for applications in medicinal chemistry and materials science.
1,4-Dioxaspiro[4.5]decane-8-carbonitrile serves as a versatile bicyclic scaffold for medicinal chemistry and process development, offering a rigid, three-dimensional core with orthogonal functional handles. The nitrile group enables direct derivatization via hydrolysis or nucleophilic addition, while the spirocyclic ether framework provides excellent metabolic stability and conformational constraint. Its bench-stable nature and compatibility with standard coupling conditions facilitate efficient library synthesis and structural diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3276
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: