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CS-W001157 4
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1-Methyl-1H-pyrazol-4-amine

  • CAS No. 69843-13-6

  • Cat. No. CS-W007391
  • Purity≥97%
  • MDL No.MFCD05667135

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1H-pyrazol-4-amine|CS-W007391

Structure of 69843-13-6

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General Information

  • CAS No. 69843-13-6
  • Cat. No. CS-W007391
  • Purity ≥97%
  • MDL No. MFCD05667135
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇N₃
  • Molecular Weight 97.12
  • Synonym(s) 1-Methyl-1H-Pyrazol-4-Ylamine; 1-Methyl-1H-pyrazol-4-amine
  • SMILES C[N]1C=C(C=N1)N

Application

1-Methyl-1H-pyrazol-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles through standard coupling and cyclization reactions. Its pyrazole core exhibits favorable bench stability and functional group tolerance, facilitating downstream modifications in API synthesis. The molecule functions effectively in amide bond formation, Suzuki couplings, and transition-metal-catalyzed transformations, supporting scalable workflows for drug discovery and process development.

Synthesis

  • Route1

    References

    • Wang, Xiaojing Patent: US2011/251176 A1, 2011 ; Location in patent: Page/Page column 160-161 ; US 20110251176 A1
  • Route2
    • In-stock
      4-Nitropyrazole|CS-W002458
      2075-46-9
    • null|null
      74-88-4
    • ~%
    • In-stock
      1-Methyl-1H-pyrazol-4-amine|CS-W007391
      69843-13-6

    References

    • WO2011/134831 A1, ; Page/Page column 36 ; WO 2011/134831 A1
  • Route3

    References

    • WO2013/17479 A1, ; Page/Page column 45 ; WO 2013/017479 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   0.0023
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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