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CS-W001157 4
Total: USD 88.00

(S)-2-(benzylamino)propan-1-ol

  • CAS No. 6940-80-3

  • Cat. No. CS-M1051
  • Purity≥97%
  • MDL No.MFCD03840382

*For research and further manufacturing use only, not for direct human use.

(S)-2-(benzylamino)propan-1-ol|CS-M1051

Structure of 6940-80-3

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General Information

  • CAS No. 6940-80-3
  • Cat. No. CS-M1051
  • Purity ≥97%
  • MDL No. MFCD03840382
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₅NO
  • Molecular Weight 165.23
  • Synonym(s) (2S)-2-(benzylamino)propan-1-ol
  • SMILES OC[C@H](C)NCC1=CC=CC=C1

Description

(S)-2-(benzylamino)propan-1-ol is a chiral amino alcohol featuring a benzylamine moiety attached to a prochiral carbon center. This configuration enables stereoselective incorporation into bioactive scaffolds, particularly in the synthesis of kinase inhibitors and neurotransmitter analogs. The molecule exhibits favorable solubility in polar solvents and stability under standard bench conditions, facilitating use in medicinal chemistry workflows.

Application

(S)-2-(benzylamino)propan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of β-amino alcohol motifs found in bioactive molecules. Its bench-stable nature and compatibility with standard functional group manipulations facilitate efficient access to diverse heterocyclic scaffolds and API intermediates through established coupling and cyclization protocols.

Synthesis

  • Route1
    • In-stock
      L-Alaninol|CS-B1303
      2749-11-3
    • null|null
      100-52-7
    • ~86%
    • In-stock
      (S)-2-(benzylamino)propan-1-ol|CS-M1051
      6940-80-3

    References

    • Janin, Yves L.; Aubertin, Anne-Marie; Chiaroni, Angele; Riche, Claude; Monneret, Claude; Bisagni, Emile; Grierson, David S. Tetrahedron, 1996 , vol. 52, # 48 p. 15157 - 15170
  • Route2

    References

    • Journal of the Chemical Society, , p. 2073,2077
  • Route3
    • 2-(Benzylideneamino)propan-1-ol|CS-0669479
      65943-49-9
    • ~%
    • In-stock
      (S)-2-(benzylamino)propan-1-ol|CS-M1051
      6940-80-3

    References

    • Synthesis, , # 6 p. 766 - 770

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   1.157
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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