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CS-W001157 4
Total: USD 88.00

Boc-L-Alaninol

  • CAS No. 79069-13-9

  • Cat. No. CS-W007729
  • Purity≥98%
  • MDL No.MFCD00043121

*For research and further manufacturing use only, not for direct human use.

Boc-L-Alaninol|CS-W007729

Structure of 79069-13-9

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General Information

  • CAS No. 79069-13-9
  • Cat. No. CS-W007729
  • Purity ≥98%
  • MDL No. MFCD00043121
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO₃
  • Molecular Weight 175.23
  • Synonym(s) None
  • SMILES CC(C)(OC(N[C@H](CO)C)=O)C

Description

Boc-L-Alaninol serves as a protected amino alcohol derivative, featuring a stable tert-butoxycarbonyl group that enables reliable handling and selective deprotection. This scaffold integrates seamlessly into peptide synthesis and small-molecule conjugation workflows, where its hydroxyl functionality offers a reactive handle for further derivatization under standard conditions.

Application

Boc-L-Alaninol serves as a stable, bench-friendly building block for peptide and heterocyclic synthesis. The Boc group provides reliable protection of the primary amine, enabling selective deprotection under mild acidic conditions. Its hydroxyl functionality supports efficient derivatization via esterification or ether formation, facilitating access to diverse molecular architectures in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Gobbini, Mauro; Armaroli, Silvia; Banfi, Leonardo; Benicchio, Alessandra; Carzana, Giulio; Fedrizzi, Giorgio; Ferrari, Patrizia; Giacalone, Giuseppe; Giubileo, Michele; Marazzi, Giuseppe; Micheletti, Rosella; Moro, Barbara; Pozzi, Marco; Scotti, Piero Enrico; Torri, Marco; Cerri, Alberto Journal of Medicinal Chemistry, 2008 , vol. 51, # 15 p. 4601 - 4608
  • Route2

    References

    • Rengasamy, Rajesh; Curtis-Long, Marcus J.; Woo, Duck Seo; Seong, Hun Jeong; Jeong, Ill-Yun; Ki, Hun Park Journal of Organic Chemistry, 2008 , vol. 73, # 7 p. 2898 - 2901
  • Route3

    References

    • Stanfield, C. Freeman; Parker, James E.; Kanellis, Panayiotis Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4799 - 4800

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   0.8919
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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