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Structure of 694-85-9
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1-Methylpyridin-2(1H)-one features a pyridinone core with a methyl group at the 1-position, delivering enhanced solubility and stability compared to unsubstituted analogs. This bench-stable heterocycle integrates readily into synthetic sequences requiring nitrogen-donor ligands or bioactive scaffolds.
1-Methylpyridin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable pyridone core with enhanced solubility and metabolic resilience. Its N-methylated pyridinone scaffold enables predictable hydrogen bonding and π–π interactions, facilitating target engagement in kinase and protease inhibitors. The compound exhibits excellent bench stability, tolerates diverse functional groups, and participates reliably in cross-coupling and nucleophilic substitution reactions, making it a practical choice for lead optimization and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: