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Structure of 952182-01-3
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4-Amino-1-methylpyridin-2(1H)-one features a pyridinone core with a methyl group at C1 and an amino substituent at C4, delivering enhanced solubility and stability. This scaffold integrates readily into medicinal chemistry campaigns, offering a polar, hydrogen-bonding handle for target engagement in kinase and epigenetic enzyme inhibition.
4-Amino-1-methylpyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling the construction of pyridone-based heterocycles through standard coupling and functionalization reactions. Its amine and carbonyl functionalities offer orthogonal reactivity for late-stage modifications, while the methyl group enhances metabolic stability and solubility. Bench-stable and readily purified by recrystallization, it functions effectively in amide bond formation, Suzuki-Miyaura couplings, and transition-metal-catalyzed transformations common to API development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: