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CS-W001157 4
Total: USD 88.00

Tetrahydro-2H-pyran-2-ol

  • CAS No. 694-54-2

  • Cat. No. CS-0015921
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tetrahydro-2H-pyran-2-ol|CS-0015921

Structure of 694-54-2

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General Information

  • CAS No. 694-54-2
  • Cat. No. CS-0015921
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₂
  • Molecular Weight 102.13
  • Synonym(s) 2-Hydroxytetrahydro-2H-pyran; 2-Hydroxytetrahydropyran; NSC 244915; Tetrahydro-2-hydroxy-2H-pyran; Tetrahydro-2H-pyran-2-ol; Tetrahydropyran-2-ol; δ-Valerolactol; 2-Tetrahydropyranol
  • SMILES OC1CCCCO1

Description

Tetrahydro-2H-pyran-2-ol serves as a robust, bench-stable protecting group for alcohols and carboxylic acids. This cyclic acetal derivative features a hydroxyl group at the C2 position, enabling selective protection under mild conditions. The structure combines high stability with straightforward deprotection via acid-catalyzed hydrolysis, making it ideal for multi-step synthetic sequences in organic and medicinal chemistry workflows.

Synthesis

  • Route1
    • null|null
      110-87-2
    • ~96%
    • In-stock
      Tetrahydro-2H-pyran-2-ol|CS-0015921
      694-54-2

    References

    • Organic Letters, , vol. 10, # 22 p. 5203 - 5206
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 61, # 17 p. 5793 - 5800
  • Route3
    • null|null
      25073-26-1
    • null|null
      201230-82-2
    • ~0%
    • In-stock
      Tetrahydro-2H-pyran-2-ol|CS-0015921
      694-54-2
    • null|null
      123703-40-2

    References

    • Organic Letters, , vol. 4, # 2 p. 289 - 291

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.5053
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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