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CS-W001157 4
Total: USD 88.00

Methyl 2-aminoisonicotinate

  • CAS No. 6937-03-7

  • Cat. No. CS-W003145
  • Purity≥97%
  • MDL No.MFCD04039316

*For research and further manufacturing use only, not for direct human use.

Methyl 2-aminoisonicotinate|CS-W003145

Structure of 6937-03-7

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General Information

  • CAS No. 6937-03-7
  • Cat. No. CS-W003145
  • Purity ≥97%
  • MDL No. MFCD04039316
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₂
  • Molecular Weight 152.15
  • Synonym(s) Methyl 2-aminopyridine-4-carboxylate
  • SMILES O=C(C1=CC(N)=NC=C1)OC

Description

Methyl 2-aminoisonicotinate features a pyridine ring bearing an amino group at the 2-position and a methyl ester at the 4-position, delivering a robust scaffold for medicinal chemistry. This electron-rich heterocycle integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability under standard conditions.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      2-Aminopyridine-4-carboxylic acid|CS-D1172
      13362-28-2
    • ~89%
    • In-stock
      Methyl 2-aminoisonicotinate|CS-W003145
      6937-03-7

    References

    • Lo Monte, Fabio; Kramer, Thomas; Gu, Jiamin; Brodrecht, Martin; Pilakowski, Johannes; Fuertes, Ana; Dominguez, Juan Manuel; Plotkin, Batya; Eldar-Finkelman, Hagit; Schmidt, Boris European Journal of Medicinal Chemistry, 2013 , vol. 61, p. 26 - 40
  • Route2

    References

    • EP1754706 A1, ; Page/Page column 76-77 ;
  • Route3
    • null|null
      107-20-0
    • In-stock
      Methyl 2-Amino-5-bromoisonicotinate|CS-D0775
      882499-87-8
    • ~89%
    • In-stock
      Methyl 2-aminoisonicotinate|CS-W003145
      6937-03-7

    References

    • NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2007/113226 A1, 2007 ; Location in patent: Page/Page column 126-127 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   0.4504
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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