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CS-W001157 4
Total: USD 88.00

(2-Aminopyridin-4-yl)methanol

  • CAS No. 105250-17-7

  • Cat. No. CS-W003117
  • Purity≥98%
  • MDL No.MFCD03791261

*For research and further manufacturing use only, not for direct human use.

(2-Aminopyridin-4-yl)methanol|CS-W003117

Structure of 105250-17-7

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General Information

  • CAS No. 105250-17-7
  • Cat. No. CS-W003117
  • Purity ≥98%
  • MDL No. MFCD03791261
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 2-amino-4-(hydroxymethyl)pyridinium
  • SMILES OCc1ccnc(c1)N

Description

4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenol is a linker containing a methyltetrazine and a hydroxy moiety. This reagent enables simple and efficient incorporation of a tetrazine moiety onto antibodies, TCO-containing peptides and other TCO-attached molecules.

Synthesis

  • Route1

    References

    • SCHERING CORPORATION Patent: WO2007/1975 A1, 2007 ; Location in patent: Page/Page column 51 ; WO 2007/001975 A1
  • Route2

    References

    • US2003/100567 A1, ;
  • Route3

    References

    • Selwood; Brummell; Budworth; Burtin; Campbell; Chana; Charles; Fernandez; Glen; Goggin; Hobbs; Kling; Liu; Madge; Meillerais; Powell; Reynolds; Spacey; Stables; Tatlock; Wheeler; Wishart; Woo Journal of Medicinal Chemistry, 2001 , vol. 44, # 1 p. 78 - 93

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.14
  • LogP   0.1561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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