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CS-W001157 4
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N-Benzylcinchonidinium chloride

  • CAS No. 69257-04-1

  • Cat. No. CS-W011649
  • Purity≥95%
  • MDL No.MFCD00082422

*For research and further manufacturing use only, not for direct human use.

N-Benzylcinchonidinium chloride|CS-W011649

Structure of 69257-04-1

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General Information

  • CAS No. 69257-04-1
  • Cat. No. CS-W011649
  • Purity ≥95%
  • MDL No. MFCD00082422
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₉ClN₂O
  • Molecular Weight 420.98
  • Synonym(s) None
  • SMILES [H][C@]12CC[N@+](C[C@H]2C=C)(CC3=CC=CC=C3)[C@@]([C@H](O)C4=CC=NC5=CC=CC=C54)([H])C1.[Cl-]

Description

N-Benzylcinchonidinium chloride serves as a chiral phase-transfer catalyst, featuring a rigid quinuclidine core and a benzyl-substituted nitrogen that enhances both solubility and enantioselectivity. This bench-stable salt integrates seamlessly into asymmetric synthesis workflows, enabling efficient stereocontrol in key C–C and C–N bond-forming reactions under mild conditions.

Synthesis

  • Route1
    • null|null
      100-44-7
    • In-stock
      Cinchonidine|CS-0007887
      485-71-2
    • ~51%
    • In-stock
      N-Benzylcinchonidinium chloride|CS-W011649
      69257-04-1

    References

    • Colonna, Stefano; Re, Alberto; Wynberg, Hans Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 547 - 552

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.8836
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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