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Structure of 6921-22-8
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2,3-Difluoronitrobenzene features a highly reactive aromatic core with two fluorine atoms and a nitro group positioned ortho to each other. This electronic configuration enhances its utility in nucleophilic aromatic substitution reactions, enabling efficient functionalization under mild conditions. The molecule exhibits excellent bench stability and compatibility with diverse reaction media, making it a reliable building block for advanced synthetic sequences in medicinal chemistry and materials science.
2,3-Difluoronitrobenzene serves as a versatile building block in nucleophilic aromatic substitution (SNAr) reactions, enabling efficient access to substituted anilines under mild conditions. Its dual fluorine substituents provide high reactivity at the ortho and meta positions relative to the nitro group, facilitating selective functionalization. The compound exhibits excellent bench stability and is compatible with a range of nucleophiles, including amines and thiols, making it well-suited for synthesizing pharmaceutical intermediates and agrochemical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: