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CS-W001157 4
Total: USD 88.00

1-Isopropylurea

  • CAS No. 691-60-1

  • Cat. No. CS-0162822
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Isopropylurea|CS-0162822

Structure of 691-60-1

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General Information

  • CAS No. 691-60-1
  • Cat. No. CS-0162822
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀N₂O
  • Molecular Weight 102.14
  • Synonym(s) Isopropylurea
  • SMILES O=C(N)NC(C)C

Description

1-Isopropylurea is a bench-stable, moisture-tolerant urea derivative featuring a branched isopropyl group that enhances solubility in polar organic solvents. This structural motif enables efficient incorporation into reaction networks requiring mild, non-nucleophilic amide functionalities.

Application

1-Isopropylurea serves as a stable, bench-ready urea derivative enabling selective amine coupling and hydrogen-bonding interactions in synthetic workflows. Its isopropyl substitution enhances solubility in organic media while maintaining compatibility with standard functional groups, facilitating use in peptide synthesis, catalyst design, and heterocycle construction.

Synthesis

  • Route1
    • null|null
      75-31-0
    • ~79%
    • In-stock
      1-Isopropylurea|CS-0162822
      691-60-1

    References

    • Chemie Linz Gesellschaft m.b.H. Patent: US5091553 A1, 1992 ;
  • Route2
    • Dimethynur|CS-0824712
      13256-32-1
    • null|null
      75-31-0
    • ~50%
    • In-stock
      1-Isopropylurea|CS-0162822
      691-60-1

    References

    • Snyder, John K.; Stock, Leon M. Journal of Organic Chemistry, 1980 , vol. 45, # 5 p. 886 - 891
  • Route3

    References

    • Gramain, Jean-Claude; Remuson, Roland Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2341 - 2346

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.0631
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

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