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CS-W001157 4
Total: USD 88.00

2,3,5,6,8,9,11,12,14,15-Decahydrobenzo[b][1,4,7,10,13,16]hexaoxacyclooctadecin-18-amine

  • CAS No. 68941-06-0

  • Cat. No. CS-0203386
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3,5,6,8,9,11,12,14,15-Decahydrobenzo[b][1,4,7,10,13,16]hexaoxacyclooctadecin-18-amine|CS-0203386

Structure of 68941-06-0

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General Information

  • CAS No. 68941-06-0
  • Cat. No. CS-0203386
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₅NO₆
  • Molecular Weight 327.37
  • Synonym(s) 4-AMINOBENZO-18-CROWN-6 SESQUIHYDRATE HYDROCHLORIDE
  • SMILES NC1=CC=C2C(OCCOCCOCCOCCOCCO2)=C1

Description

Bis(2-methoxyethyl)amine can be used as a reactant:In the Pd-catalyzed Buchwald-Hartwig amination reaction to synthesize aryl amines by reacting with aryl and heteroaryl halides.To synthesize -ketoamides via metal-free oxidative coupling reaction with methyl ketones in the presence of tert-butyl hydroperoxide as an oxidant and iodine as a catalyst.To synthesize N, N-dialkyl perfluoroalkanesulfonamides by reacting with perfluoroalkanesulfonyl halides.To synthesize N-(alkoxy)succinamide ester by reacting with succinyl chloride, which can be used as an intermediate to prepare diol monomer for biodegradable polyester synthesis.

Synthesis

  • Route1

    References

    • Dykes, Graham M.; Smith, David K. Tetrahedron, 2003 , vol. 59, # 22 p. 3999 - 4009
  • Route2

    References

    • Acta Chimica Academiae Scientiarum Hungaricae, , vol. 110, # 1 p. 25 - 28
  • Route3
    • 2,2'-(1,2-Phenylenebis(oxy))diethanol|CS-W010540
      10234-40-9
    • ~%
    • In-stock
      2,3,5,6,8,9,11,12,14,15-Decahydrobenzo[b][1,4,7,10,13,16]hexaoxacyclooctadecin-18-amine|CS-0203386
      68941-06-0

    References

    • Journal of Organic Chemistry USSR (English Translation), , vol. 18, p. 1305 - 1307 Zhurnal Organicheskoi Khimii, , vol. 18, # 7 p. 1495 - 1498

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   81.4
  • LogP   1.1064
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   0

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