Fmoc-L-Val-OH

Name: Fmoc-L-Val-OH
Brand: ChemScene
Availability: InStock
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CAS No. 68858-20-8
Cat. No. CS-W009099
Purity≥97%
MDL No.MFCD00037124

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 68858-20-8

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General Information

CAS No. 68858-20-8
Cat. No. CS-W009099
Purity ≥97%
MDL No. MFCD00037124
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₂₁NO₄
Molecular Weight None
Synonym(s) FMOC-L-valine; Fmoc-valine
SMILES CC(C)[C@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C(O)=O

Description

Fmoc-L-Val-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a fluorenylmethoxy carbonyl (Fmoc) protecting group. This orthogonal protection enables efficient solid-phase peptide synthesis, where the side chain remains inert under standard deprotection conditions. The valine residue offers moderate hydrophobicity and steric bulk, ideal for incorporating into bioactive sequences.

Synthesis

Route1
- 851713-90-1
- ~81%
- In-stock
  
  68858-20-8
References
- Sedighi, Minoo; Lipton, Mark A. Organic Letters, 2005 , vol. 7, # 8 p. 1473 - 1475
Route2
- In-stock
  
  86060-87-9
- ~%
- In-stock
  
  68858-20-8
References
- EP1757568 A1, ; Page/Page column 7 ;
Route3
- In-stock
  
  72-18-4
- In-stock
  
  82911-69-1
- ~86%
- In-stock
  
  68858-20-8
References
- Lapatsanis, Lucas; Milias, George; Froussios, Kleanthis; Kolovos, Miltiadis Synthesis, 1983 , # 8 p. 671 - 673

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 75.63
LogP 3.6343
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 5

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Valine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-L-Val-OH

CAS No. 68858-20-8

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