Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Chloro-4-cyanopyridine

  • CAS No. 68325-15-5

  • Cat. No. CS-W003228
  • Purity≥98%
  • MDL No.MFCD05663706

*For research and further manufacturing use only, not for direct human use.

3-Chloro-4-cyanopyridine|CS-W003228

Structure of 68325-15-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 68325-15-5
  • Cat. No. CS-W003228
  • Purity ≥98%
  • MDL No. MFCD05663706
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClN₂
  • Molecular Weight 138.55
  • Synonym(s) 3-Chloroisonicotinonitrile
  • SMILES N#Cc1ccncc1Cl

Description

3-Chloro-4-cyanopyridine is a heterocyclic building block featuring a chlorine atom at the 3-position and a cyano group at the 4-position of the pyridine ring. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, facilitating rapid access to complex pharmaceutical intermediates under standard conditions.

Application

3-Chloro-4-cyanopyridine serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds through palladium-catalyzed cross-coupling and nucleophilic substitution reactions. Its dual functional groups—electrophilic chlorine and electron-withdrawing nitrile—offer orthogonal reactivity for sequential transformations. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and API intermediate synthesis.

Synthesis

  • Route1
    • null|null
      14906-59-3
    • ~63%
    • In-stock
      3-Chloro-4-cyanopyridine|CS-W003228
      68325-15-5

    References

    • Leroy; Bigan; Blondeau Synthetic Communications, 1997 , vol. 27, # 17 p. 2905 - 2916
  • Route2

    References

    • Cailly, Thomas; Fabis, Frederic; Rault, Sylvain Tetrahedron, 2006 , vol. 62, # 25 p. 5862 - 5867
  • Route3
    • null|null
      620535-14-0
    • ~%
    • In-stock
      3-Chloro-4-cyanopyridine|CS-W003228
      68325-15-5

    References

    • Organic and Biomolecular Chemistry, , vol. 11, # 15 p. 2466 - 2472

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   36.68
  • LogP   1.60668
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 3-Chloro-4-cyanopyridine sigma3-Chloro-4-cyanopyridine manufacturer3-Chloro-4-cyanopyridine price3-Chloro-4-cyanopyridine structure3-Chloro-4-cyanopyridine SDSbuy 3-Chloro-4-cyanopyridine3-Chloro-4-cyanopyridine supplier3-Chloro-4-cyanopyridine uses3-Chloro-4-cyanopyridine molecular weightprice of 3-Chloro-4-cyanopyridine3-Chloro-4-cyanopyridine chemical name formula of 3-Chloro-4-cyanopyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label