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CS-W001157 4
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3-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid

  • CAS No. 683218-80-6

  • Cat. No. CS-0154453
  • Purity≥97%
  • MDL No.MFCD01861819

*For research and further manufacturing use only, not for direct human use.

3-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid|CS-0154453

Structure of 683218-80-6

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General Information

  • CAS No. 683218-80-6
  • Cat. No. CS-0154453
  • Purity ≥97%
  • MDL No. MFCD01861819
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₄
  • Molecular Weight 229.27
  • Synonym(s) 3-TERT-BUTOXYCARBONYLAMINO-3-CYCLOPROPYL-PROPIONIC ACID
  • SMILES CC(C)(OC(NC(C1CC1)CC(O)=O)=O)C

Description

This cyclopropylpropanoic acid derivative features a tert-butoxycarbonyl-protected amine group, enabling straightforward incorporation into peptide synthesis workflows. The sterically constrained cyclopropyl moiety enhances conformational rigidity, while the Boc handle ensures stability under standard bench conditions.

Application

3-((tert-Butoxycarbonyl)amino)-3-cyclopropylpropanoic acid serves as a versatile building block for peptide synthesis and medicinal chemistry, enabling the introduction of a cyclopropyl-substituted aliphatic amine motif. The Boc-protected amine and carboxylic acid functionality offer orthogonal reactivity, facilitating sequential coupling steps. Its bench-stable nature and compatibility with standard deprotection protocols support efficient synthesis of complex scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.7644
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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