Boc-Phe(4-Cl)-OH

Name: Boc-Phe(4-Cl)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 68090-88-0
Cat. No. CS-W008486
Purity≥97%
MDL No.MFCD00057808

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 68090-88-0

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Description

Boc-Phe(4-Cl)-OH features a para-chlorophenylalanine residue with a tert-butoxycarbonyl protecting group, enabling stable incorporation into peptide chains. The electron-withdrawing chlorine substituent enhances synthetic handling and modulates reactivity during coupling steps. This bench-stable building block supports efficient solid-phase peptide synthesis workflows.

Application

Boc-Phe(4-Cl)-OH serves as a versatile building block in peptide synthesis, enabling efficient incorporation of 4-chlorophenylalanine into target sequences. The Boc group provides robust protection under standard deprotection conditions, while the para-chlorophenyl side chain offers enhanced metabolic stability and modulated electronic properties. This derivative exhibits excellent bench stability, facilitates straightforward purification, and participates reliably in coupling reactions with minimal epimerization.

General Information

CAS No. 68090-88-0
Cat. No. CS-W008486
Purity ≥97%
MDL No. MFCD00057808
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₁₈ClNO₄
Molecular Weight None
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=C(Cl)C=C1)NC(OC(C)(C)C)=O

Computational Chemistry Data

TPSA 75.63
LogP 2.8604
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Boc-Phe(4-Cl)-OH

CAS No. 68090-88-0

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