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2-Methyl-1-(methylamino)propan-2-ol

  • CAS No. 67622-86-0

  • Cat. No. CS-0038213
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyl-1-(methylamino)propan-2-ol|CS-0038213

Structure of 67622-86-0

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General Information

  • CAS No. 67622-86-0
  • Cat. No. CS-0038213
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO
  • Molecular Weight 103.16
  • Synonym(s) 1,1-dimethyl-2-methylaminoethanol
  • SMILES CC(C)(CNC)O

Description

2-Methyl-1-(methylamino)propan-2-ol features a tertiary alcohol scaffold flanked by a methylamino group, delivering enhanced solubility and stability under standard bench conditions. This structure enables direct integration into polar reaction media without decomposition, facilitating efficient coupling in synthetic workflows requiring robust amine functionality.

Application

2-Methyl-1-(methylamino)propan-2-ol serves as a stable, bench-ready building block for the synthesis of β-amino alcohols and related heterocyclic scaffolds. Its tertiary alcohol functionality enables straightforward derivatization, while the pendant methylamino group offers compatibility with standard coupling and protection strategies. The molecule exhibits good solubility in common organic solvents and demonstrates robust stability under routine handling conditions, facilitating its use in iterative synthetic sequences and medicinal chemistry lead optimization workflows.

Synthesis

  • Route1
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      2-Methyl-1-(methylamino)propan-2-ol|CS-0038213
      67622-86-0

    References

    • Goldberg; Ringk; Spoerri Journal of the American Chemical Society, 1939 , vol. 61, p. 3562 Full Text View citing articles Show Details Novocol Chem.Mfg.Co. Patent: US2252713 , 1938 ;
  • Route2
    • null|null
      50-00-0
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      75-86-5
    • ~%
    • In-stock
      2-Methyl-1-(methylamino)propan-2-ol|CS-0038213
      67622-86-0
    • In-stock
      1-(Dimethylamino)-2-methylpropan-2-ol|CS-0147115
      14123-48-9

    References

    • du Pont de Nemours and Co. Patent: US2462736 , 1944 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.0233
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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