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Structure of 67318-11-0
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Ethyl 5-aminothiophene-2-carboxylate features a thiophene core with strategically positioned amino and ester functionalities, enabling direct incorporation into heterocyclic scaffolds. The electron-rich thiophene ring enhances reactivity in transition-metal-catalyzed couplings, while the amino group offers sites for derivatization. This bench-stable intermediate supports efficient synthesis of bioactive molecules and functional materials.
Ethyl 5-aminothiophene-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophenes via palladium-catalyzed cross-coupling and electrophilic substitution. The amino and ester functionalities offer orthogonal reactivity for sequential derivatization, while the molecule exhibits excellent bench stability and facilitates straightforward purification. This compound functions as a key intermediate in the construction of bioactive scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: