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Structure of 5734-67-8
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4-Chloro-6-ethylpyrimidin-2-amine features a pyrimidine core bearing chloro and ethyl substituents at the 4- and 6-positions, respectively, with a primary amine at C2. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and tunable solubility for drug discovery applications.
4-Chloro-6-ethylpyrimidin-2-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chlorine at C4 facilitates palladium-catalyzed cross-coupling reactions, while the amino group at C2 supports derivatization via alkylation, acylation, or electrophilic substitution. The ethyl substituent enhances lipophilicity and metabolic stability, offering favorable properties for drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: