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Structure of 670256-21-0
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4-Bromo-2-(hydroxymethyl)benzoic acid features a strategically positioned bromine atom and a hydroxymethyl group flanking a carboxylic acid moiety, enabling selective functionalization in synthetic routes. This scaffold supports efficient derivatization under standard conditions, offering enhanced solubility and stability for use in pharmaceutical intermediates and bioconjugation applications.
4-Bromo-2-(hydroxymethyl)benzoic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. The carboxylic acid group enables direct derivatization via amide, ester, or acyl chloride formation, while the bromine facilitates palladium-catalyzed cross-coupling reactions. The hydroxymethyl functionality offers orthogonal reactivity for oxidation to aldehyde or carboxylic acid, or protection as ethers. Bench-stable and readily purified by recrystallization, it supports scalable synthesis of functionalized aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: