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Structure of 7697-32-7
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4-Bromo-3,5-dimethylbenzoic acid features a bromine substituent flanked by two methyl groups on a benzoic acid scaffold, delivering enhanced lipophilicity and steric bulk. This configuration supports efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring defined electronic and steric profiles.
4-Bromo-3,5-dimethylbenzoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-methyl groups provide steric shielding and enhance bench stability, while the carboxylic acid functionality facilitates direct derivatization or activation for amide and ester formation. The bromine substituent offers reliable coupling compatibility in Suzuki, Stille, and Negishi transformations, making it a practical choice for constructing complex aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: