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CS-W001157 4
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1-(4-(Aminomethyl)phenyl)ethan-1-one hydrochloride

  • CAS No. 66522-66-5

  • Cat. No. CS-0101890
  • Molecule weightNone
  • Purity≥90%
  • MDL No.MFCD06797813

*For research and further manufacturing use only, not for direct human use.

1-(4-(Aminomethyl)phenyl)ethan-1-one hydrochloride|CS-0101890

Structure of 66522-66-5

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General Information

  • CAS No. 66522-66-5
  • Cat. No. CS-0101890
  • Purity ≥90%
  • MDL No. MFCD06797813
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClNO
  • Molecular Weight None
  • Synonym(s) 4-ACETYLBENZYLAMINE HYDROCHLORIDE
  • SMILES CC(C1=CC=C(CN)C=C1)=O.[H]Cl

Description

This aryl ketone derivative features a para-aminomethyl group enabling direct conjugation or derivatization. The hydrochloride salt enhances solubility and stability in aqueous systems, facilitating use in synthetic transformations and bioconjugation workflows under standard conditions.

Application

1-(4-(Aminomethyl)phenyl)ethan-1-one hydrochloride serves as a versatile synthetic building block for constructing aryl ketone-containing scaffolds in medicinal chemistry. Its amine-functionalized side chain enables facile derivatization via reductive amination, amidation, or electrophilic substitution. The hydrochloride salt enhances solubility and stability during storage and handling, facilitating use in standard solution-phase reactions. Functions effectively in the synthesis of bioactive heterocycles and targeted API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   1.7697
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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