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Structure of 66500-55-8
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1,4-Dioxaspiro[4.5]decane-8-carboxylic acid is a rigid, spirocyclic diether with a pendant carboxylic acid group. This structural motif combines enhanced stereochemical stability with a polar functional handle, enabling its use in constrained molecular scaffolds for medicinal chemistry and macrocyclic synthesis.
1,4-Dioxaspiro[4.5]decane-8-carboxylic acid serves as a rigid, bicyclic scaffold for medicinal chemistry and synthetic intermediates. Its spirocyclic architecture provides conformational constraint, while the carboxylic acid functionality enables direct derivatization or incorporation into bioactive molecules via standard coupling reactions. The molecule exhibits good bench stability and functional group tolerance, facilitating use in multi-step syntheses and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: