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CS-W001157 4
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2-(2,6-Difluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole

  • CAS No. 66464-26-4

  • Cat. No. CS-0503751
  • Molecule weight211.21
  • Purity≥98%
  • MDL No.MFCD27927162

*For research and further manufacturing use only, not for direct human use.

2-(2,6-Difluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0503751

Structure of 66464-26-4

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General Information

  • CAS No. 66464-26-4
  • Cat. No. CS-0503751
  • Purity ≥98%
  • MDL No. MFCD27927162
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁F₂NO
  • Molecular Weight 211.21
  • Synonym(s) Oxazole, 2-(2,6-difluorophenyl)-4,5-dihydro-4,4-dimethyl-
  • SMILES CC1(C)N=C(C2=C(F)C=CC=C2F)OC1

Synthesis

  • Route1
    • 2,6-Difluoro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide|CS-0513500
      150079-31-5
    • ~89%
    • 2-(2,6-Difluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0503751
      66464-26-4

    References

    • MERCK SHARP and DOHME LIMITED Patent: WO2005/28445 A2, 2005 ; Location in patent: Page/Page column 31 ; WO 2005/028445 A2
  • Route2

    References

    • Meyers,A.I.; Williams,B.E. Tetrahedron Letters, 1978 , p. 223 - 226

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.59
  • LogP   2.5202
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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