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CS-W001157 4
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2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole

  • CAS No. 66464-20-8

  • Cat. No. CS-0454707
  • Molecule weight193.22
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0454707

Structure of 66464-20-8

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General Information

  • CAS No. 66464-20-8
  • Cat. No. CS-0454707
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂FNO
  • Molecular Weight 193.22
  • Synonym(s) 2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline
  • SMILES CC1(C)COC(=N1)C2=CC=CC=C2F

Synthesis

  • Route1
    • 4,4-Dimethyl-2-phenyl-4,5-dihydrooxazole|CS-0320752
      19312-06-2
    • ~42%
    • 2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0454707
      66464-20-8

    References

    • Bellamy, Estelle; Bayh, Omar; Hoarau, Christophe; Trecourt, Francois; Queguiner, Guy; Marsais, Francis Chemical Communications, 2010 , vol. 46, # 37 p. 7043 - 7045
  • Route2
    • 2-Fluoro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide|CS-0276191
      128764-53-4
    • ~80%
    • 2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0454707
      66464-20-8

    References

    • Sedinkin, Sergey L.; Rath, Nigam P.; Bauer, Eike B. Journal of Organometallic Chemistry, 2008 , vol. 693, # 18 p. 3081 - 3091
  • Route3
    • null|null
      179116-95-1
    • ~97%
    • 2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole|CS-0454707
      66464-20-8

    References

    • Peer, Markus; De Jong, Johannes C.; Kiefer, Matthias; Langer, Thomas; Rieck, Heiko; Schell, Heico; Sennhenn, Peter; Sprinz, Juergen; Steinhagen, Henning; Wiese, Burkhard; Helmchen, Guenter Tetrahedron, 1996 , vol. 52, # 21 p. 7547 - 7583

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.59
  • LogP   2.3811
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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