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CS-W001157 4
Total: USD 88.00

(S)-(1-Methylpyrrolidin-2-yl)methanamine

  • CAS No. 66411-54-9

  • Cat. No. CS-0053063
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-(1-Methylpyrrolidin-2-yl)methanamine|CS-0053063

Structure of 66411-54-9

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Description

(S)-(1-Methylpyrrolidin-2-yl)methanamine is a chiral amine scaffold featuring a sterically defined pyrrolidine ring with a methylated nitrogen and a methylene-linked amine. This configuration imparts enhanced solubility and directional reactivity, enabling efficient coupling in asymmetric synthesis. The molecule serves as a modular building block for bioactive compound libraries, particularly in medicinal chemistry applications requiring precise stereocontrol.

Application

(S)-(1-Methylpyrrolidin-2-yl)methanamine serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through amine-based coupling reactions. Its pyrrolidine core provides favorable solubility and metabolic stability, while the (S)-configuration ensures stereochemical fidelity in target compounds. The molecule exhibits bench stability, ease of purification, and compatibility with standard functional group transformations, making it ideal for use in API development and fragment-based drug discovery workflows.

General Information

  • CAS No. 66411-54-9
  • Cat. No. CS-0053063
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄N₂
  • Molecular Weight 114.19
  • Synonym(s) 1-[(2S)-1-Methyl-2-pyrrolidinyl]methanamine
  • SMILES CN1CCC[C@H]1CN

Computational Chemistry Data

  • TPSA   29.26
  • LogP   0.0393
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group :
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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