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CS-W001157 4
Total: USD 88.00

4-Bromobenzene-1,3-diol

  • CAS No. 6626-15-9

  • Cat. No. CS-W008238
  • Purity≥95%
  • MDL No.MFCD00002272

*For research and further manufacturing use only, not for direct human use.

4-Bromobenzene-1,3-diol|CS-W008238

Structure of 6626-15-9

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General Information

  • CAS No. 6626-15-9
  • Cat. No. CS-W008238
  • Purity ≥95%
  • MDL No. MFCD00002272
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrO₂
  • Molecular Weight 189.01
  • Synonym(s) 4-Bromoresorcinol
  • SMILES OC1=CC=C(Br)C(O)=C1

Description

A competitive, cell-permeable, and irreversible inhibitor of caspases -1, -4, and -5

Application

4-Bromobenzene-1,3-diol serves as a versatile building block for the synthesis of functionalized aromatic scaffolds, enabling direct coupling reactions via palladium-catalyzed cross-coupling protocols. Its ortho-diol functionality offers enhanced solubility and stability compared to related phenols, while the bromine substituent provides reliable reactivity in Suzuki, Stille, and Negishi couplings. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • null|null
      108-46-3
    • ~99%
    • In-stock
      4-Bromobenzene-1,3-diol|CS-W008238
      6626-15-9

    References

    • Synthetic Communications, , vol. 37, # 2 p. 323 - 328
  • Route2

    References

    • Journal of the Indian Chemical Society, , vol. 14, p. 725,731
  • Route3
    • 4,6-Dibromobenzene-1,3-diol|CS-0193273
      61524-51-4
    • ~60%
    • In-stock
      4-Bromobenzene-1,3-diol|CS-W008238
      6626-15-9

    References

    • Canadian Journal of Chemistry, , vol. 66, p. 2431 - 2439

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.8603
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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