2-Methoxy-4-pyridinol

Name: 2-Methoxy-4-pyridinol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 66080-45-3
Cat. No. CS-B0744
Purity≥96%
MDL No.MFCD12546434

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 66080-45-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 66080-45-3
Cat. No. CS-B0744
Purity ≥96%
MDL No. MFCD12546434
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇NO₂
Molecular Weight 125.13
Synonym(s) 4-Pyridinol, 2-Methoxy-
SMILES COC1=CC(O)=CC=N1

Description

2-Methoxy-4-pyridinol features a pyridinol core with strategically positioned methoxy and hydroxyl groups, enabling versatile participation in transition-metal-catalyzed couplings. The electron-rich aromatic system enhances reactivity in cross-coupling processes, while the ortho-hydroxyl facilitates chelation in catalytic cycles. This bench-stable compound serves as a key building block for functionalized heterocycles in medicinal chemistry and materials science.

Application

2-Methoxy-4-pyridinol serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through electrophilic substitution and coupling reactions. Its methoxy group enhances solubility and modulates electronic properties, while the phenolic hydroxyl facilitates derivatization via etherification or esterification. Bench-stable and compatible with standard synthetic protocols, it functions effectively in multistep synthesis of heterocyclic intermediates and API precursors.

Synthesis

Route1
- 66080-44-2
- ~99%
- In-stock
  
  66080-45-3
References
- Daiichi Sankyo Company, Limited Patent: EP2404918 A1, 2012 ; Location in patent: Page/Page column 34 ;
Route2
- In-stock
  
  53937-02-3
- ~%
- In-stock
  
  66080-45-3
References
- EP2404918 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 42.35
LogP 0.7958
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Methoxy-4-pyridinol sigma2-Methoxy-4-pyridinol manufacturer2-Methoxy-4-pyridinol price2-Methoxy-4-pyridinol structure2-Methoxy-4-pyridinol SDSbuy 2-Methoxy-4-pyridinol2-Methoxy-4-pyridinol supplier2-Methoxy-4-pyridinol uses2-Methoxy-4-pyridinol molecular weightprice of 2-Methoxy-4-pyridinol2-Methoxy-4-pyridinol chemical name formula of 2-Methoxy-4-pyridinol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Methoxy-4-pyridinol

CAS No. 66080-45-3

Recommended Products