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CS-W001157 4
Total: USD 88.00

3-Pyrrolidinophenylboronic acid

  • CAS No. 659731-18-7

  • Cat. No. CS-W004233
  • Purity≥98%
  • MDL No.MFCD03095125
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Pyrrolidinophenylboronic acid|CS-W004233

Structure of 659731-18-7

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Description

3-Pyrrolidinophenylboronic acid features a pyrrolidine ring conjugated to a boronic acid group, enabling efficient Suzuki-Miyaura cross-coupling reactions. The electron-rich aromatic system enhances reactivity, while the boronic acid moiety offers stable, moisture-tolerant handling under standard conditions. This compound integrates readily into complex molecular architectures for pharmaceutical and materials synthesis.

Application

3-Pyrrolidinophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its pyrrolidine moiety enhances solubility and stability compared to simpler arylboronic acids, while maintaining compatibility with diverse reaction conditions. The compound functions reliably in late-stage functionalization and is well-suited for medicinal chemistry applications requiring robust boronate handles.

General Information

  • CAS No. 659731-18-7
  • Cat. No. CS-W004233
  • Purity ≥98%
  • MDL No. MFCD03095125
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BNO₂
  • Molecular Weight 191.04
  • Synonym(s) (3-PYRROLIDIN-1-YLPHENYL)BORONIC ACID
  • SMILES OB(c1cccc(c1)N1CCCC1)O

Computational Chemistry Data

  • TPSA   43.7
  • LogP   -0.0334
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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