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CS-W001157 4
Total: USD 88.00

3-Pyrrolidinophenylboronic acid

  • CAS No. 659731-18-7

  • Cat. No. CS-W004233
  • Purity≥98%
  • MDL No.MFCD03095125

*For research and further manufacturing use only, not for direct human use.

3-Pyrrolidinophenylboronic acid|CS-W004233

Structure of 659731-18-7

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General Information

  • CAS No. 659731-18-7
  • Cat. No. CS-W004233
  • Purity ≥98%
  • MDL No. MFCD03095125
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₄BNO₂
  • Molecular Weight 191.04
  • Synonym(s) (3-PYRROLIDIN-1-YLPHENYL)BORONIC ACID
  • SMILES OB(c1cccc(c1)N1CCCC1)O

Description

3-Pyrrolidinophenylboronic acid features a pyrrolidine ring conjugated to a boronic acid group, enabling efficient Suzuki-Miyaura cross-coupling reactions. The electron-rich aromatic system enhances reactivity, while the boronic acid moiety offers stable, moisture-tolerant handling under standard conditions. This compound integrates readily into complex molecular architectures for pharmaceutical and materials synthesis.

Application

3-Pyrrolidinophenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its pyrrolidine moiety enhances solubility and stability compared to simpler arylboronic acids, while maintaining compatibility with diverse reaction conditions. The compound functions reliably in late-stage functionalization and is well-suited for medicinal chemistry applications requiring robust boronate handles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.7
  • LogP   -0.0334
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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