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Structure of 65938-77-4
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5-Methyl-2-pyridinesulfonamide features a pyridine ring bearing a methyl group at the 5-position and a sulfonamide moiety at the 2-position, delivering enhanced solubility and stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in kinase inhibitor design and other medicinal chemistry applications.
5-Methyl-2-pyridinesulfonamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine sulfonamide core exhibits favorable bench stability, moderate solubility, and compatibility with common protecting group strategies. The methyl substituent enhances lipophilicity and provides a handle for further derivatization, while the sulfonamide group offers strong hydrogen-bonding capacity and metabolic stability, making it a practical scaffold for targeted compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: